TXA Posted bynorcalemsjmJanuary 13, 2022January 13, 2022Posted inUncategorized Tranexamic Acid – TXA The number of attempts remaining is 4 1 / 14 All ALS organizations are required to conduct a 100% review of all prehospital TXA administrations. True False 2 / 14 In the CRASH 2 study there was an increase in the mortality rate for patients who received TXA greater than 3 hours after the traumatic event. True False 3 / 14 TXA leads to the formation of fibrin which is the ‘mesh’ that impedes blood flow for the formation of a clot. True False 4 / 14 TXA is a synthetic amino acid (lysine) that blocks plasminogen from being converted to the enzyme plasmin (the enzyme that halts the clotting process)? True False 5 / 14 Which of the following is a possible side effect of TXA: Acute gastrointestinal disturbances Visual disturbances Thromboembolic events (DVT, PE, etc.) All of the above 6 / 14 Which of the following is the correct procedure for administration of TXA IV/IO push as rapidly as possible IV/IO push over 2 minutes Mix appropriate dose of TXA with 100 mL or 250 ml bag D5W or NS and infuse over 10 minutes Mix appropriate dose of TXA with 1000 mL NS or LR and run wide open 7 / 14 What is the correct dose of TXA: 0.5gm 1 gm 100 gm 8 / 14 Which one of the following is not a contraindication for administration of TXA: Time since injury > 3 hours Isolated traumatic brain injury Thromboembolic event (i.e. stroke, MI, PE, DVT) within the past 24 hours Traumatic arrest with > 5 minutes of CPR without ROSC Patient has no visible bleeding 9 / 14 Which of the following is an indication for administration of TXA under Nor-Cal EMS standing order treatment protocol: Blunt or penetrating traumatic injury with signs and symptoms of hemorrhagic shock (including SBP < 90) Hemorrhage not controlled with direct pressure, hemostatic agents, or commercial tourniquet application both a and b 10 / 14 What is the minimum patient age for administration of TXA under Nor-Cal EMS standing order treatment protocol? none 12 years old 15 years old 18 years old 11 / 14 Which one of the following describes the mechanism of action of TXA Synthetic derivative of lysine that inhibits fibrinolysis by blocking the lysine binding sites on plasminogen Inhibits both plasminogen activation and Plasmin activity thus preventing clot breakdown Catalyzes the conversion of plasminogen to plasmin Both a and b 12 / 14 Which one of the following is not a contributing factor to trauma-associated hyperfibrinolysis: Vasodilation Blood loss Dysfunction of coagulation factors due to hypothermia and acidosis 13 / 14 The coagulation process is sometimes described as a ‘cascade’ because chemicals called clotting factors prompt reactions that activate additional clotting factors True False 14 / 14 Which of the following is not one of the three steps/items needed to achieve hemostasis: Vascular spasm Platelet plug formation Administration of crystalloid IV fluid boluses Coagulation Your score is 0% Restart quiz Send feedback Share this:TwitterFacebookLike this:Like Loading...